We reported differences in gene expression/methylation between human adipose tissue depots. These data add weight to the hypothesis that distinct molecular mechanisms in fat depots contribute to the observed clinical consequences. We hypothesize that RNA modifications may be fat depot specific and may play an important role in establishing fat depot specific gene expression. We perform m6Aseq and expect specific patterns that translate into depot-specificity.
Gunnar Mellgren, Johan Fernø.
University of Bergen, Haukeland Hospital, Norway.
Tom Mala, Jon Kristinsson.
Aker Hospital, Oslo, Norway.
Housheng Hansen He.
University of Toronto, Canada.
University of Leipzig, Germany.
Geir Slupphaug, Cathrine B. Vågbø.
NTNU Trondheim, Norway
Project start: 01.08.2018
Project end: 31.07.2021